汪 超

教授，PI

博士生导师

课题组网页

教育与科研经历：

        2010年获苏州大学生物科学专业学士学位；2014年获苏州大学化学生物学专业博士学位；2015年至2018年在美国北卡罗来纳州立大学（NCSU）与教堂山分校（UNC）从事博士后研究工作。2018年6月加入苏州大学功能纳米与软物质研究院，被聘为教授、博士生导师，入选国家优青、江苏省特聘教授。

研究领域与研究成果：

课题组长期围绕生物材料与免疫工程交叉领域，利用工程学和材料学的技术手段，发展了一系列通用化平台技术，通过设计新型工程化生物材料、构建智能递释系统、发展创新生物技术，提出了多种疾病免疫治疗技术的新策略，为解决免疫治疗面临的共性问题和挑战提供了新的思路。迄今为止在国际学术期刊共发表SCI论文100余篇，以通讯作者在Nature Communications、Science Advances、Cell Reports等学术刊物上发表论文40余篇，H-index 75，申请多项发明专利，目前授权7项，转让1项。作为项目负责人主持国家重点研发计划青年项目、基金委优秀青年科学基金等。

学术荣誉与人才计划：

[1] JNB Rising Star Award (2023)

[2] Clarivate Analytics “全球高被引科学家” (2018-2022)

[3] MIT Technology Review Innovators Under 35 (TR35) Asia Pacific (2021)

[4] World's Top 2% Scientists (2019-2021)

[5] 江苏省“创新创业”人才 (2019)

[6] 江苏省“六大人才高峰”高层次人才 (2019)

[7] 江苏省特聘教授 (2018)

[8] 江苏省科学技术一等奖（4/5） (2017)

[9] CASNN Rising Star Award (2019)

[10] Biomaterials Future Scientist Award (2017)

[11] 教育部自然科学二等奖（4/4） (2014)

招生方向与招聘信息：

        本课题组热忱欢迎有志从事科研工作的本科/硕士/博士研究生以及博士后研究员到课题组学习工作；博士后：拟招收1-2名博士后研究人员，要求易于沟通，可以协助指导研究生。待遇优厚。如有兴趣，请联系cwang@suda.edu.cn。

代表性论文:（Upon arriving at Soochow Univ.）

[18] Qianyu Yang, Huaxing Dai, Beilei Wang, Jialu Xu, Yue Zhang, Yitong Chen, Qingle Ma, Fang Xu, Haibo Chen, Dongdong Sun*, Chao Wang*. Nanoplastics Shape Adaptive Anticancer Immunity in the Colon in Mice. Nano Letters, (2023).

[17] Qianyu Yang#, Huaxing Dai#, Ying Cheng#, Beilei Wang, Jialu Xu, Yue Zhang, Yitong Chen, Fang Xu, Qingle Ma, Fang Lin* and Chao Wang*. Oral Feeding of Nanoplastics affects Brain function of Mice by Inducing Macrophage IL-1 signal in Intestine. Cell Reports, 42, 112346 (2023).

[16] Yitong Chen, Yue Zhang, Beilei Wang, Qin Fan, Qianyu Yang, Jialu Xu, Huaxing Dai, Fang Xu, Chao Wang*. Blood Clot Scaffold Load with Liposome Vaccine and siRNAs Targeting PD-L1 and TIM-3 for Effective DC Activation and Cancer Immunotherapy. ACS Nano, 17, 760 (2023). Link

[15] Fang Xu*, Yi Wu, Qianyu Yang, Ying Cheng, Jialu Xu, Yue Zhang, Huaxing Dai, Beilei Wang, Qingle Ma, Yitong Chen, Fang Lin, Chao Wang*. Engineered extracellular vesicles with SHP2 high expression promote mitophagy for Alzheimer’s disease treatment. Advanced Materials, 2207107, (2022). Link

[14] Beilei Wang, Jinyu Bai*, Bo Tian, Hao Chen, Qianyu Yang, Yitong Chen, Jialu Xu, Yue Zhang, Huaxin Dai, Qingle Ma, Ziyin Fei, Heng Wang, Fang Xu, Xiaozhong Zhou*, Chao Wang*. Genetically Engineered Hematopoietic Stem Cells Deliver TGF-β Inhibitor to Enhance Bone Metastases Immunotherapy. Advanced Science, 2201451 (2022). Link

[13] Jialu Xu, Qingle Ma, Yue Zhang, Ziying Fei, Yifei Sun, Qin Fan, Bo Liu, Jinyu Bai, Yue Yu, Jianhong Chu*, Jingrun Chen*, Chao Wang*. Yeast-derived nanoparticles remodel the immunosuppressive microenvironment in tumor and tumor-draining lymph nodes to suppress tumor growth. Nature Communications, 13, 110 (2022). Link

[12] Huaxing Dai, Qin Fan, Ziying Fei, Qingle Ma, Qianyu Yang, Jiacheng Chu, Xuanfang Zhou, Yue Zhang, Ziliang Dong, Fang Xu, Beilei Wang, Rong Sun, Yifan Shen, Ruao Xie, Ruibin Li and Chao Wang*. Systemically Administered Silica Nanoparticles Result in Diminished T cell Response in Lung. Nano Today 42, 101332 (2022). Link

[11] Qin Fan#, Huaxing Dai#, Jinyu Bai#, Jialu Xu, Qingle Ma, Ziying Fei, Xiaozhong Zhou*, Kam W. Leong*, Chao Wang*. Degradation-resistant Implanted Biomaterials Establish an Immunosuppressive Microenvironment that Induces T Cell Exhaustion by Recruiting Myeloid Cells. Fundamental Research (2022). Link

[10] Fang Xu, Ziying Fei, Huaxing Dai, Jialu Xu, Qin Fan, Shufang Shen, Yue Zhang, Qingle Ma, Jiacheng Chu, Fei Peng, Fangfang Zhou, Zhuang Liu, Chao Wang*. Mesenchymal Stem Cell-derived Extracellular Vesicles with High PD-L1 Expression for Autoimmune Diseases Treatment. Advanced Materials, 34, 2106265 (2022). Link

[9] Yue Zhang, Jialu Xu, Ziying Fei, Huaxing Dai, Qin Fan, Qianyu Yang, Yitong Chen, Beilei Wang, Chao Wang*. 3D Printing Scaffold Vaccine for Antitumor Immunity. Advanced Materials, 33, 2106768 (2021). Link

[8] Shufang Shen, Huaxing Dai, Ziying Fei, Yu Chai, Yu Hao, Qin Fan, Ziliang Dong, Yujie Zhu, Jialu Xu, Qingle Ma, Xiao Han, Ligeng Xu, Fei Peng, Zhuang Liu, Chao Wang*. Immunosuppressive Nanoparticles for Management of Immune-Related Adverse Events in Liver. ACS Nano, 5, 9111 (2021). Link

[7] Qin Fan, Jinyu Bai, Huajian Shan, Ziying Fei, Hao Chen, Jialu Xu, Qingle Ma, Xiaozhong Zhou* and Chao Wang*. Implantable Blood Clot Loaded with BMP-2 for Regulation of Osteoimmunology and Enhancement of Bone Repair. Bioactive Materials, 6, 4014 (2021). Link

[6] Ziying Fei, Qin Fan*, Huaxing Dai, Xuanfang Zhou, Jialu Xu, Qingle Ma, Atsushi Maruyama*, Chao Wang*. Physiologically Triggered Injectable Red Blood Cell-Based Gel for Tumor Photoablation and Enhanced Cancer Immunotherapy. Biomaterials, 271, 120724 (2021). Link

[5] Qin Fan, Qingle Ma, Jinyu Bai, Jialu Xu, Ziying Fei, Ziliang Dong, Atsushi Maruyama, Kam W. Leong, Zhuang Liu and Chao Wang*. An Implantable Blood Clot-based Immune Niche for Enhanced Cancer Vaccination. Science Advances, 6, eabb4639 (2020). Link[Biotechscope]

[4] Qingle Ma, Qin Fan, Jialu Xu, Jinyu Bai, Xiao Han, Ziliang Dong, Xiaozhong Zhou, Zhuang Liu, Zhen Gu* and Chao Wang*. Calming Cytokine Storm in Pneumonia by Targeted Delivery of TPCA-1 Using Platelet-derived Extracellular Vesicles. Matter, 3, 287 (2020). Link[Matter]

[3] Xuanfang Zhou, Zhouqi Meng*, Jialin She, Yaojia Zhang, Xuan Yi, Hailin Zhou, Jing Zhong, Ziliang Dong, Xiao Han, Muchao Chen, Qin Fan, Kai Yang and Chao Wang* . Near-Infrared Light-Responsive Nitric Oxide Delivery Platform for Enhanced Radioimmunotherapy. Nano-Micro Letters, 12, 100 (2020).

[2] Lin Zhang, Jinhua Zhou, Lvzhong Hu, Xiao Han, Xinwei Zou, Qian Chen, Youguo Chen*, Zhuang Liu*, Chao Wang*. In Situ Formed Fibrin Scaffold with Cyclophosphamide to Synergize with Immune Checkpoint Blockade for Inhibition of Cancer Recurrence after Surgery. Advanced Functional Materials, 1906922 (2019). 

[1] Xiao Han#, Shufang Shen#, Qin Fan, Guojun Chen, Edikan Archibong, Gianpietro Dotti, Zhuang Liu*, Zhen Gu* and Chao Wang*. Red Blood Cell Derived Nanoerythrosome for Antigen Delivery with Enhanced Cancer Immunotherapy. Science Advances, 5, eaaw6870 (2019).

所有文章列表：

https://scholar.google.com/citations?user=t3ljbdoAAAAJ&hl

联系方式：cwang@suda.edu.cn

责任编辑：杨娟